The study team interviewed 52 ladies and 49 males from the tribe, aged 18 to 55. The interviews occurred in Swahili and the voices of the women and men were recorded. When the recordings were studied it was discovered that the deep voiced males had fathered more children than the non-deep voiced guys; the man with the deepest voice got ten surviving children, as the one with the highest pitched voice had just three. Apicella suggests that the men with the low pitched voices possibly had higher testosterone amounts, which attracted them more to females or made them more appealing to them. Apicella says it is also a possibility that men with higher testosterone amounts start reproducing previous in life and could also be better hunters.The entire survival advantage with TAS-102 was seen in essentially all prespecified subgroups , including subgroups described according to each one of the three stratification elements . In the multivariate Cox regression analysis, none of the elements were identified as becoming predictive; all P values for treatment conversation were more than 0.20. Three factors were identified as prognostic: time since diagnosis of 1st metastasis, ECOG performance status, and number of metastatic sites. Nevertheless, the magnitude of the TAS-102 treatment impact, after adjustment for all three factors, was maintained . In particular, the efficacy of TAS-102 was documented in patients with disease that were refractory to fluorouracil when that medication had been administered as an element of the last treatment routine before study access and in sufferers who experienced previously been treated with regorafenib.